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ACTOFLORFEN
Oral solution 
(For vet. use only)

ACTOFLORFEN

Each 1ml contains:
Florfenicol   23 mg.
Florfenicol is a broad-spectrum synthetic antibiotic in the phenicol group that is active against most Gram-positive and Gram-negative bacteria isolated from domestic animals.
Florfenicol acts by inhibition of protein synthesis at the ribosomal level and is bacteriostatic.
However, bactericidal activity has been demonstrated in-vitro against Actinobacillus pleuropneumoniae and Pasteurella multocida when florfenicol is present at concentrations above the MIC for up to 12 hours.
In-vitro testing has shown that florfenicol is active against the bacterial pathogens most commonly isolated in respiratory diseases in pigs, including Actinobacillus pleuropneumoniae and Pasteurella multocida.
Swine: Treatment of swine respiratory disease associated with Actinobacillus pleuropneumoniae and Pasteurella multocida susceptible to florfenicol.
Orally in drinking water
Dose:
0.44 ml of Actoflorfen per kg of body weight per day for 5 consecutive days.
- A slight reduction of water consumption by the animals, dark brown faeces and constipation may be observed during treatment. Commonly observed adverse effects are diarrhoea and/or peri-anal and rectal erythema/oedema which may affect approximately 40% of the animals.
- These effects are transient.
- In a few of the affected animals prolapse of the rectum that resolves without treatment may be observed.
- In case of overdosing, a decrease in weight gain, food and water consumption, peri-anal erythema and edema and modification of some hematological and biochemical parameters indicative of dehydration may be observed.
- Its use is not recommended during gestation and lactation.
- Use of the product should be based on susceptibility testing.
- Inappropriate use of the product may increase the prevalence of bacteria resistant to florfenicol.
- Treatment should not exceed 5 days.
- The medicated drinking water should be replaced every 24 hours.
- Do not use in boars intended for productive purposes.
- Do not administer in cases of previous allergic reactions to florfenicol.
Meat & Offal: 20 days.
Store at a temperature not exceeding 30°C and used for 30 days after opening to be stored at a temperature not exceeding 30°C.
HDPE plastic bottles capped with (HDPE) plastic caps with internal LDPE foam linear, filled with 100 ml, 250 ml, 500 ml and 1000 ml oral solution with an outer label.

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