Indication: 

Broilers Chickens 
Treatment of chronic respiratory disease (CRD) caused by Mycoplasma gallisepticum in chickens.   
Pigs:
Treatment of swine dysentery Caused by Brachyspira hyodysenteriae 
Treatment of enzootic pneumonia Caused by Mycoplasma hyopneumoniae    

Composition:
Each 1 gm contains: 
Tylosin tartarate 872.88 mg (eq.to tylosin base 750 mg)   Properties: -Tylosin is a macrolide antibiotic produced by a strain of Streptomyces fradiae. - At normal doses, tylosin has a bacteriostatic action.  It inhibits the synthesis of proteins susceptible organisms by binding to 50S ribosomal subunits and blocking the step translocation.   Tylosin binds reversibly to the 23S rRNA in the 50S ribosome subunit and inhibit mRNA-directed protein synthesis. They also stimulate the dissociation of peptidyl-tRNA from ribosomes during translocation. Tylosin has spectrum activity includes Gram-positive bacteria such as Clostridium perfringens and some Gram-negative strains such as Pasteurella and Mycoplasma spp. at concentrations of 16µg/ml or less.   

Target species: 
Broilers Chickens and pigs.   

Dosage of Administration:   
Route: Orally via drinking water. 
For Whole Product 
Broilers Chickens: 
1.2 – 2 gm / liter per day added to the drinking water for 2  to 5 days   
Pigs: 
40 – 80 mg / kg of body weight per day.  Use only medicinal water for 3 to 10 days maximum.   

Warning and precautions: - 
It is advisable to periodically check the susceptibility of isolated pathogens in vitro. - The drinking water facilities (water tank, pipes, nipples etc...) must be carefully cleaned after the end of treatment.    


Contra - Indications: 
Do not administer to laying hens producing eggs for human consumption. 
Do not use in animals with known hypersensitivity to Tylosin 
Do not administer Tylosin with coccidiostats feed additives because Tylosin is compatible with most coccidiostats feed additives.   
Do not administer Tylosin  with lincomycin which may lead to antagonism   

Adverse Effects: 
n rare cases, anal irritation, manifested by agitation of the tail, erythema, swelling of the anal mucosa and rectal prolapse is possible  
  
Withdrawal times: 
Slaughter chickens, pigs: 1 day.   

Storage conditions: 
Store at temperature not exceeding 30ºC, in dry place and to be used immediately after opening and reconstitution .   

Packaging: 
Plastic jar (HDPE)  contains 10, 20,30,50,100,150,200,250,300,500,1000gm of  powder +aluminum seal + (HDPE) plastic cap with safety seal+ inner leaflet .